Laurence Lee

February 5, 2023 in Supplements

Brain supplements, often known as nootropics, are natural supplements that aim to boost brain function in healthy people.

Memory, attention, motivation, productivity, and general cognitive function may improve with the right brain supplements. Nootropics may potentially boost long-term brain health by preventing age-related deterioration.

But with so many memory pills and brain supplements on the market, selecting the perfect one for your requirements may be difficult.

We want to assist you in making your decision, so we analyzed the top brain pills on the market to determine which ones are the most effective and provide the best bargain. Each nootropic was assessed based on its components, dose, reviews, and price.

Our top recommendations for the finest brain health supplements in 2022 are listed below.

Best Brain Boosting Supplements Pills



Strongest Nootropics Stack


Mind Lab Pro

Best for anxiety and brain fog


Alpha Brain

Best for memory and focus



Best tailored nootropic


Qualia Mind

Best for 40+ men

Noocube: Most Powerful Nootropics Blend

NooCube is a supplement manufactured by Wolfson Berg Ltd, a respected firm that has produced some of the most popular supplements on the market, including testosterone boosters, legal steroids, and fat burners.

Experts developed this brain enhancer using a formulation developed by neuroscientists and thoroughly investigated and tested. 

It comprises seven quality components that are professionally known to be safe for human consumption.

NooCube aids with increasing work capacity, multifunctional skills, memory, cognitive function, and focus.

It works to increase neurotransmitter synthesis and supports neuron development and regeneration in the brain.

It is free of any dangerous substances and unpleasant side effects. As the brand is confident in the product, they also provide a 60-day money-back guarantee. They deliver anywhere, and each bottle has a 30-day supply. When you buy many bottles in bulk, you may avail of a slew of perks and offers.

When your vessels are healthy, you will experience a marked improvement in your memory, attention, and mental alertness.

Pros and Cons Of Noocube


  • A reputed brand using natural and clinically supported ingredients.
  • There is a plethora of scientific data supporting the formula's effectiveness.
  • There are no recognized adverse effects.
  • Huge savings on bulk purchases.
  • Worldwide delivery is free.
  • Helpful in improving cognitive capacities.
  • Organic ingredients clinically demonstrated to be beneficial.
  • A potent blend of the most effective brain-boosting chemicals.
  • Caffeine and genetically modified creatures are not present. It elevates one's mood and alleviates tension.


  • There is no comprehensive description of what all of the components accomplish.
  • It is pricey unless purchased in bulk.
  • Can be bought only from the official site.

Ingredients in Noocube

  • Alpha Glyceryl Phosphorylcholine (Alpha GPC): Alpha GPC stimulates the synthesis of certain neurotransmitters called acetylcholine and dopamine within the brain. Thus, choline is released. It is a type of choline that can help boost energy. Acetylcholine production aids in the regeneration of brain cells. While, Dopamine improves the brain's focus, motivation, and mood. Alpha GPC is well known for enhancing cognitive performance. It also aids in the treatment of neurodegenerative diseases such as Alzheimer's.
  • Oatmeal Straw: Oat straw is produced from wild green oats and is in use for a long time as a brain stimulant. It is frequently associated with the treatment of skin disorders. Several studies have found that oat straw increases alpha-2 waves in the brain, enhancing blood flow to the brain.
  • Cat’s Claw: Uncaria tomentosa, often known as Cat's Claw, is thought to be an antioxidant that protects the brain from free radical damage. Cat's claw also aids in the reduction of brain plaque, and the improvement of memory, mental clarity, and attention.
  • Bacopa Monnieri: Bacopa Monnieri is an Indian herb that contains bacosides, which are compounds that may aid in the healing of damaged neurons and the formation of new cells. It’s shown to increase the number of dendrites in the brain's nerve tissues. It aids in the healing of injured neurons and the regeneration of nerves. It enhances cognitive function while also treating memory and issues with anxiety.
  • Huperzine A: It is a component derived from an Asian moss that can help in the inhibition of acetylcholine breakdown, hence improving focus, memory, and mental clarity.
  • L-tyrosine and L-theanine: They are amino acids that can improve energy, attention, and cognitive performance. They can also help with anxiety and stress reduction.

Mind Lab Pro: Best for Stress and Brain Fog

Mind Lab Pro is a high-quality nootropic from Opti-Nutra, a well-known producer of quality nutritional supplements. According to the company, Mind Lab Pro was created to increase cognition, attention, and other cognitive functions.

It was also created to protect the brain from stress and damage caused by aging and pollutants. Mind Lab Pro contains 11 quality brain boosters, vitamins, and minerals. No additives, allergies, pesticides, or other potentially hazardous ingredients.

Mind Lab Pro is intended to enhance many cognitive processes such as motivation, attention, memory, and relaxation under stressful situations. A smart drug with 11 eleven active ingredients.

Mind Lab Pro prioritizes quality. All components get evaluated for active nootropic levels. Also, third-party quality control for a final assessment. They also disclose all ingredients and doses since they feel that transparency is essential when selecting a product for your brain.

Mind Lab Pro is available via the official website. You may purchase in volume to obtain big discounts and freebie goods. There's a 60-day money-back guarantee if you don't get the results you want.

Pros and Cons Of MindLab Pro


  • Made entirely of natural components.
  • No record of adverse effects..
  • Developed to promote brain health, cognitive function, and stress tolerance in people of all ages.
  • Can be taken throughout the day to keep your brain in peak condition.
  • Can be purchased from any location on the planet.
  • Money-back guarantee of 60 days.
  • Exceptional Nootropic Supplement, Universally Applicable.
  • This product contains 11 high-quality, organic, natural components.
  • This product contains no allergies, GMOs, gluten, caffeine, artificial flavors and colors, preservatives, or prohibited components.


  • When compared to other possibilities, it is a bit pricey.
  • It does not mix well with other nootropic pills.
  • Only available for purchase on their website.
  • Customers have expressed unhappiness with shipping and customer service issues.

Ingredients in Mind Lab Pro

When purchasing a product for your body and mind, you should prioritize transparency. Mind Lab Pro understands this. Thus, they provide all of the label information, including ingredients and doses, so you can buy with confidence. The following are the ingredients:

  • Citicoline as Cognizin, 250mg: Aids in brain cell repair and regeneration, and also neurotransmitter stimulation. Cognizin® is a proprietary version of citicoline that has been shown to increase brain energy by %, improve memory, cognition, concentration, attentiveness, and even emotional balance.
  • Phosphatidylserine, 100mg: Associated in the production of specific neurotransmitters, helps in memory formation and slows mental impairment. It might likewise help with attitude, mental alertness, and anxiety.
  • Bacopa Monnieri, 150mg: These are antioxidants that protect the brain from the effects of aging. According to studies, they enhance memory span recall, quick recall memory, and learning.
  • Lion’s Mane Mushroom, 500mg: This ingredient is credited with brain cell repair and growth. According to research, it may be effective for repairing nerves and improving cognitive function. It may also help with mood.
  • L-Theanine, 100mg, and L-Tyrosine, 175mg: These amino acids can help reduce anxiety, improve attention, and create specific transmitters, among other things. They can assist the brain work better amid excessive stress, sleeplessness, or weariness.
  • Rhodiola Rosea 50mg: It's a plant that can aid with exhaustion, sadness, and anxiety, and also increase cognitive performance, focus, and calm thinking under stressful settings.
  • Maritime Pine Bark Extract, 75mg: An antioxidant that aids in the reduction of damaging free radicals in the body, allowing your body and brain to work better, have more energy, and focus better.
  • Vitamin B6, 2.5mg. Vitamin B9, 100 mcg, and Vitamin B12, 7.5 mcg: The B vitamins support cognitive performance and are an essential cornerstone to producing many crucial chemicals in the body. They aid with blood flow and brain synthesis.

Alpha Brain: Best for Cognitive Memory

Onnit's Alpha Brain is a compound nootropic. It's a combination of three formulations that Onnit explored for specialized purposes.

Combining these three recipes with Cat's Claw can help with stress and depression swings. It can also help with focus and mental vigor.

The Onnit Flow Blend works with certain brain pathways that have been shown to improve mood levels in studies. Flow Blend contains both theanine and L-tyrosine, shown to help with chemicals in the brain involved in anxiety and reward.

The Onnit Focus Blend contains a researched substance that boosts acetylcholine, an important molecule for nerve function. This combination can help your brain's neurons perform more efficiently. The Onnit Fuel Blend serves as an energy boost for your cognitive capabilities, assisting you in staying focused.

Pros and Cons of Alpha Brain


  • Improved memory and recall.
  • There is reduced stress.
  • Better mood and clarity of mind.
  • Brain processes are quick.
  • Feel some diminished mental strain.
  • Ingredients benefit in the regulation of serotonin and dopamine.
  • Acetylcholine increased.
  • Improved concentration and motivation.
  • The 3-in-1 recipe produces the best outcomes.
  • There is a broad range of dietary supplements available.


  • There is a caution to keep youngsters away from it.
  • Before consuming, ask a doctor if you are breastfeeding or pregnant.
  • There is no whole vitamin regimen.
  • Because of the overproduction of neurotransmitters in your nerve cells, you may experience sleeping issues if you take it late in the day.
  • It is not available at large-scale shops or physical pharmacies.
  • Some people may experience mild nausea when taking it.

Ingredients in Alpha Brain

We investigated each of the elements in the Onnit Alpha Brain combination and discovered plenty to appreciate. The research on the various constituents has been substantial, and we have offered some perspective into all of them.

  • L-Theanine and L-Tyrosine: The Flow Blend were researched for their ability to moderate mood by assisting the brain in the regulation of serotonin and dopamine. Both can alleviate stress and stabilize your mood.
  • Oat Straw Extract: For years, it has been used in herbal remedies to enhance oxygen flow in the brain, which aids in all cognitive and emotional functions.
  • Phosphatidylserine: One of the most researched supplements for brain performance, this nootropic may have the finest track record for enhancing cognition and short-term mental concentration and performance.
  • Alpha GPC: This is a choline molecule required for brain function. Choline is needed for many tasks, but it is especially significant as a nootropic since it acts as a protective coating for neurons.
  • Huperzia Serrata: Helps in complex bodily function. ACT, or acetylcholine, is the 'trigger' that causes nerves and neurons to fire. Another molecule, AChE, is responsible for the breakdown of acetylcholine in human bodies. Huperzia Serrata suppresses AChE production so that it can increase the available ACT in the body.
  • Bacopa Extract: A bark that has been used in Eastern medicine to aid brain function.
  • L-Leucine: An important amino acid that can activate a variety of processes, including blood sugar regulation.
  • Toothed Clubmoss: An organic cholinesterase inhibitor, commonly known as huperzine A. It prevents the breakdown of choline, which promotes memory and protects nerve cells from damage. There is some evidence that huperzine A aids in the reduction of cognitive decline linked with Alzheimer's disease.
  • Pterostilbene: A key element of blueberries, it has been examined for anti-cancer properties.

Thesis: Best Customized Nootropic

Unlike many of the supplements we reviewed, Thesis requires you to take a customized questionnaire before using their product. Although no one enjoys taking a questionnaire, we found the approach to be simple and only took around 2 minutes.

The benefit of taking the customized quiz is that the items you receive from Thesis come tailored to your specific requirements. Then again, buying a bunch of acuity vitamins won't benefit you if you don't dither and have sharp concentration.

You not only receive the benefits you need with Thesis, but you also save money by not paying for and getting stuff you do not need. They also offer special mixtures of certain nootropics depending on individual requirements, such as anxiety and brain fog in this case.

They offer a 30-day money-back guarantee on their website. In addition, if you subscribe, you will receive a $60 discount on your very first order. The one-month supply comes with a free tracker notebook, free shipping, and even a free coach.

Pros and Cons in Thesis

After completing a tailored questionnaire, the user is given a free baseline.


  • Caffeine-free alternatives are available.
  • A personalized formula backed by hundreds of studies.
  • It also includes expert instruction from recognized specialists.
  • Money-back guarantee - 30 days.
  • Thesis curates your blends so you don't squander money on unnecessary ingredients.
  • Choose from five different formulae to properly pinpoint which components of your brain operate best for you. Motivation, Creativity, Logic, Energy, and Clarity.
  • Thesis provides transparency by indicating which components are used and their quantity.
  • Pick from caffeine-containing or caffeine-free formulas.


  • Formula recirculation.
  • A month is needed to find out its effectiveness.
  • There is no option for a free trial. They do, however, provide a complete refund with no questions asked.
  • The price of the item. You pay $80 each month even if you choose the Subscribe & Save option.
  • As a result, they're one of the more costly nootropics available.

Ingredients In Thesis

These ingredients are only instances of what appeared in the model quiz since Thesis applies four separate supplements to address the various regions in the tailored question. Each ingredient list is located under the recipe for a specified purpose.

Formula for Clarity

  • Lion's Mane is a fungus that has long been used in Japan to aid brain function; some research suggests it may help preserve neural connections.
  • Epicatechin, a natural antioxidant present in chocolate, red wine, and tea, aids vascular function by transporting nutrients to the right places.
  • Alpha GPC aids in the conversion of choline into the vital acetylcholine required for biological functioning.
  • 7,8-DHF, commonly known as Dihydroflavone, is a chemical that aids in brain cellular communication.


  • The body uses NAC, or N-acetyl cysteine, to ensure that antioxidants are used correctly.
  • Citicoline is a supplement that can improve mental capabilities and cognitive restoration due to aging.
  • NALT (N-Acetyl-L-tyrosine) is an amino acid recognized to promote attentiveness, alertness, and focus.
  • Sabroxy® is a patented nootropic pill that enhances short-term memory and general cognitive performance. Derived from the Indian trumpet tree.
  • TeaCrine is a patented product, same as Theacrine, a caffeine alternative found in nature.
  • Zynamite® is a well-researched mango leaf extract that has been shown to boost cognitive and personal vitality and performance.


  • Artichoke Extract is a natural medicine for hangovers and heart disease for millennia. It is one of the most effective medicinal herbs in scientific trials.
  • Dynamine derives from the kucha tea leaf and, like TeaCrine, provides theacrine-like energy properties.
  • Forskolin, produced from the mint family, has been believed to help with anything from asthma to weight reduction in Southeast Asia for generations.
  • L-Phenylalanine is an essential alpha-amino acid that has been shown to improve mental acuity and mood, particularly when used in conjunction with any weight loss or dieting program.
  • L-Phenylalanine is an important alpha-amino acid that has been shown to increase mental clarity and mood, particularly when used in conjunction with any weight-loss or mood-improvement program.
  • Vitamin B12 is essential for correctly metabolizing lipids and amino acids into useful energy rather than storing them as fats or amino acids.


  • DHA is an omega-3 fatty acid that has been linked to a lower inflammatory response and improved cardiovascular responses, particularly in the brain.
  • Ginkgo Biloba has been shown to boost people's dopamine responses, which improves their mental abilities.
  • Phosphatidylserine interacts with the Ginkgo because it inhibits cortisone, dopamine's antagonist.
  • Synapsa®, or Bacopa Monnieri Extract, is said to help with all aspects of brain function.
  • Theobromine and Ginkgo act together to increase dopamine responsiveness.
  • TAU (tri acetyl uridine) is a supplement that promotes the production of ribonucleic acid, which can help preserve neuropathways.


  • Ashwagandha: The evergreen plant Ashwagandha grows across Asia and Africa. Chemicals in ashwagandha relax the mind, lower blood pressure, and transform immunity. It aids in the reduction of stress, anxiety, cortisol levels, and stress-related desires for food. Aids in the improvement of memory and cognitive function.
  • Panax Ginseng: The plant Panax ginseng may be found in Korea, China, and Siberia. It supports recollection and mental abilities. It also helps with Alzheimer's disease, depression, and a variety of other issues.
  • Zembrin: Zembrin is an extract of the South African shrub S. tortuosum, which has been farmed for centuries. It enhances attention, boosts mood, and lowers stress. Has anti-stress qualities, as well as relaxation, serenity, motivation, and vigor. It also promotes sleep.
  • Agmatine Sulfate: Agmatine is a compound observed in bacteria, plants, and animals, as well as humans. It is formed from the amino acid arginine. It influences learning and memory by regulating some of the mechanisms involved. Agmatine appears to be a promising therapy option for behavioral and neurodegenerative problems.
  • Alpha GPC: Alpha-GPC has often been used for treating Alzheimer's disease, stroke, dementia caused by the decreased blood supply to the brain, memory and thinking skills, and other conditions.

Qualia Mind: Best for Enhancing Mental Focus

Qualia Mind is a nootropic supplement from the Qualia cognitive brand created by Neurohacker Collective. It was produced after doing an extensive study with leading scientists to verify and evaluate its efficiency.

Qualia Mind is one of the best nootropic pills for enhancing your brain's immediate and long-term functioning.

It has twenty-eight natural ingredients, like vitamins, nootropics, amino acids, antioxidants, adaptogens, and herbal tonics, to help you boost your performance in many aspects of your life. There's also a caffeine-free variant.

The brain supplement may be mailed anywhere in the globe, and there is a 100-day money-back guarantee if you don't get the results you want. Every container provides 22 servings, which will last 28 days, as per the manufacturer.

Pros and Cons of Qualia Mind


  • Focus, clarity, memory, energy, willpower, and creativity are all enhanced.
  • There are no negative side effects.
  • Combination of natural ingredients.
  • The company has backed research to show the product's efficacy.
  • For your first order, they provide a 100-day money-back guarantee.
  • It enhances mental stamina and focus.
  • There is also a caffeine-free version.


  • Has a daily dosage of 7 Qualia Mind Capsules, which is rather high.
  • Pretty costly, but with subscriptions and deals, you can save a lot of money.

Ingredients in Qualia Mind

This product contains twenty-eight natural ingredients, including:

  • Vitamin C: This vitamin is necessary for a variety of biological activities, including brain health.

  • Vitamin D3: A fat-soluble vitamin that protects the nervous system and has antioxidant properties.

  • B-Complex Vitamins: B vitamins are essential for the body's energy generation as well as a variety of other functions.

  • Acetyl-L-Carnitine HCI: It is an amino acid that aids in the synthesis of neurotransmitters.

  • Artichoke Leaf Extract: This is an antioxidant that can also help you produce more bile.

  • Bacopa Monnieri Leaf Extract: This component boosts the number of dendrites in the brain tissue, which increases several forms of intelligence.

  • Rhodiola Rosea Root Extract: Rhodiola Rosea Root Extract is a plant that has been shown to improve cognitive function and mental performance. It can help you feel more energized while also reducing anxiety and despair.

  • Dl-Phenylalanine: This is a vital chemical building block that helps the body produce a variety of neurotransmitters.

  • Uridine Monophosphate: This molecule is critical for the formation of RNA, which is vital to your body's survival.

  • N-Acetyl-Tyrosine: It is a form of tyrosine that assists in neurotransmitter synthesis and can help reduce anxiety.

  • Taurine: There are a variety of internal chemical and biological processes that require this amino acid.

  • L-Theanine: Additionally, this amino acid can help with anxiety, attention, and cognitive functioning.

  • Alpha-GPC: This is a kind of choline that can aid in the repair and development of brain cells and provide energy.

  • Cognizin: It is a kind of citicoline that aids in creating choline and other compounds.

  • Organic Coffee Berry: This is an antioxidant that works to protect the body from free radicals.

  • Velvet Bean Seed Extract: This is a traditional medication that contains powerful antioxidants.

  • Phosphatidylserine: This component is involved in the release of various neurotransmitters and is known to help in memory production.

  • Theobromine: It is a mild stimulant that operates in the same manner as caffeine does. It gives you a gradual, low-energy boost that lasts a long period while also boosting blood flow to your brain.

  • Docosahexaenoic Acid (DHA): This is a form of omega-3 fatty acid with a beneficial effect on the brain.

  • Celastrus Paniculatus Seed Extract: Another traditional medication with neuroprotective properties is Celastrus Paniculatus Seed Extract.

  • Ginkgo Biloba: This component is well-known for its high antioxidant content, capacity to open blood arteries leading to the brain, and ability to reduce inflammation.

  • Coleus Forskohlii: This plant extract may be able to stop an enzyme from degrading acetylcholine, a choline-derived molecule.

  • Pyrroloquinoline Quinone (PQQ): It is a neuroprotective and antioxidant compound.

  • Huperzine A: It’s a substance that inhibits the breakdown of acetylcholine.

Final Thoughts

Researching the best nootropics for you is essential if you wish to find the one that works best for you. You should now have a better idea of what some of the best products are and how they can benefit you.

About the author 

Laurence Lee

Lee is a neuroscientist who has dedicated his career to understanding the inner workings of the brain. He has seen firsthand the power of these supplements in improving cognitive function and believes that more people should be aware of their benefits. In his articles, Lee shares his extensive knowledge on the subject and provides unbiased reviews of different products.

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