Laurence Lee

February 5, 2023 in Supplements

The concept of nootropics has been the center of some heated debates over the years as some swear by its effects and others contest the theory altogether. Nevertheless, several aids on the market claim to elevate cognition, one of the most popular being Alpha Brain, an all-natural brain enhancer that has sold over a million bottles since its release.

The supplement has been endorsed by thousands of customer reviews. However, the most compelling testament comes from the notorious podcaster and comedian Joe Rogan. Joe mentioned that Alpha Brain helped him recall words better and form sentences more easily on and off-air, describing his experience with Alpha Brain in detail several times as nothing short of amazing.

Let's find out more about Alpha Brain below:

What is Alpha Brain?

Alpha Brain is an original creation formulated by world-renowned supplement manufacturer Onnit. Onnit is known for its extensively researched, expert formulated supplements containing a unique blend of FDA-approved components with excellent safety and efficacy profiles.

Alpha Brain encapsulates the brand's expertise as it has a distinct formula that contains a potent nootropic blend.

The nutrient-rich formula increases mental and physical energy, improving complete cognitive function. Studies state that Alpha Brain enhances consciousness, which supports better thinking speed/flexibility and learning in less than 6 weeks.

It also improves focus, working/verbal memory, self-control, and executive function. In addition, it improves mental processing and flow state removing brain fog/mental fatigue.

Why Get an Alternative?

Although Alpha Brain is a safe and effective supplement that produces potent effects and a comprehensive set of benefits, the product might not fully cater to different user specifications. Some users may be looking for a more affordable option, specific effects/mental influence, while others might have used the product and found the results unsatisfactory or the effects incompatible.

This is where alternatives come in. There are currently several supplements available on the market that can be used as an alternative to Alpha Brain. 

Let's take a closer look at them below:

Alpha Brain Alternatives



Best for Memory and Learning



Best for Brain Health/Nutrition


MindLab Pro

Best for the Enhancing Cognitive Function


Qualia Mind

Best for Concentration and Focus


Brain Pill

Best for Restoring/Maintaining Optimal Brain Function

1. Noocube: Best for Memory and Learning

Manufactured by Wolfson Brand Limited, Noocube is a natural supplement that contains several evidence-backed nootropics in clinically sound doses.  The supplement has an excellent safety profile which allows long and short-term use. Its core function promotes concentration, focus, memory, and decision-making.

The formula also encourages the presence of Alpha waves leading users into stable flow state, which allows users to perform at full mental capacity.

Noocube regulates mental/physical stamina while eliminating stress, mental fatigue, and brain fog. It positively affects communication and moods, naturally inducing calm and creativity, allowing the brain to efficiently absorb new information.

In addition to the direct impact on mental and cognitive health, Noocube also has neuroprotective features that guard the brain against age-related mental decline, brain disease, and cell damage. It also promotes neurotransmitter production, supporting rapid communication between different brain cells, enhancing productivity and alertness. 

Want to find out more? Read our full NooCube review here.

Pros and Cons


  • Promotes mental energy while decreasing brain fog, stress, and mental fatigue.
  • Improves thinking, memory recall, concentration, and emotional responses
  • Contains a comprehensive set of evidence-backed nootropic components
  • Supports full cognitive, mental, and physical capabilities
  • Enhances problem-solving/decision-making skills


  • Cognitive effects take time to be seen
  • Consistent use is required

2. Vyvamind: Best for Brain Health/Nutrition

Vyvamind is an all-natural neurostimulator created by SAP Nutra. The uniquely structured aid is considered a safe alternative to amphetamine-based supplements like Adderall due to its potent effects. The broad-spectrum, high-performance product can be used by all adults looking to improve mental processes.

The allergen-free, non-GMO formula removes unwarranted impulses, distractions, and mental blocks by optimizing brain processes and keeping the mind in focus mode.

It supports communication between brain cells, nerves, and neurotransmitters to eliminate brain fog/fatigue. Vyvamind elevates mental energy levels, prolonging concentration durations while encouraging self-control.

The evidence-backed ingredients in the formula also support cerebral blood flow and chemical flow. The formula helps repair damaged brain cells and promotes neuroplasticity and productivity. The product increases creativity, learning, neuron protection, and overall cognitive while preventing structural changes or cognitive decline that occur during aging.

Want to find out more? Read our full Vyvamind review here.

Pros and Cons


  • Encourages cerebral blood flow and prevents brain/mental deterioration
  • Promotes mental energy while preventing brain fog/fatigue
  • Non-GMO and allergen-free natural formula
  • Enhances mental processes and cognition
  • Prolongs concentration, memory, focus
  • It supports better moods and self-control


  • Doses must be taken regularly to accumulate benefits—effective results
  • It may cause headaches for some users

3. MindLabPro: Best for the Enhancing Cognitive Function

Designed and manufactured by Opti-Nutra Limited, MindLabPro, is a nootropic aid made using natural ingredients proven safe and effective for brain enhancement. The supplement's clean formula aims to enhance cognitive processes while restoring balance to the brain.

The formula uses a maximum potency approach with each Nutri-Capsule containing high amounts of nootropic compound for rapid effects. 

This optimizes brain function, which promotes mental energy, verbal fluidity, clarity, memory,  creativity, focus, and attention spans. MindLab supports oxygen supply to the brain by increasing cerebral blood flow.

It also encourages specific neurotransmitter activity and triggers nerve growth while improving neuron communication and working memory. In addition, MindLabPro contains neuroprotective properties, which prevent internal and external damage or injury.

Want to find out more? Read our full MindLabPro review here.

Pros and Cons


  • Promotes overall brain health, focus, and reaction speeds
  • Protects the brain from chemical/physical injuries
  • Contains natural, clinically researched ingredients
  • Promotes memory, learning, and mental energy
  • Regulates moods/emotions


  • Supplement use must be cycled
  • Not all ingredients in the formula are present in clinically approved/effective doses

4. Qualia Mind: Best for Concentration and Focus

Qualia Mind is a brain enhancement supplement that belongs to the Neurohacker Collection. The supplement uses natural ingredients to elevate cognitive function without causing brain or body discomfort.

The neuro-vitamins, antioxidants, and herbal extracts in the formula support short and long-term mental goals as well as overall brain health.

The supplement bridges nutritional gaps, providing the brain with a surplus of energy that encourages better mental performance. It promotes concentration, focus, clarity, creativity, motivation, and mental energy while eliminating the possibility of brain fog.

Qualia also prevents procrastination and improves memory, learning, and alertness. The fast-acting formula has neuroprotective benefits that fully shield the brain from damage or disease. The supplement also supports adaptive mental change and increases mental endurance, allowing users to handle stress more appropriately.

Pros and Cons


  • Natural ingredients, research-backed formula that boosts brain nutrition
  • Triggers creativity and provides mental clarity, focus
  • Removes brain fog and decreases procrastination
  • Improves mental energy and intensifies willpower


  • Possibility of side effects
  • Effectiveness of product decreases with long term use

5. Brain Pill: Best for Restoring/Maintaining Optimal Brain Function

Brain Pill is a cognitive aid that uses a unique blend of natural ingredients to improve overall mental functionality and brain health.

Each ingredient in the formula is scientifically backed and supplies the brain with a sturdy foundation of vitamins and minerals to restore/maintain brain cells' quality and function, which positively affects different aspects of cognition.

The supplement reduces brain fog and counteracts mental fatigue while providing neuroprotective benefits that protect against mental decline by directing better blood flow to the brain. It also improves learning abilities, focus, memory, and rapid recall.

The distinct formula provides users with other benefits that affect overall body functioning and physical capabilities as well.

Want to find out more? Read our full Brain Pill review here.

Pros and Cons


  • Improves focus, learning abilities, memory, and rapid recall
  • Provides nutritional benefits and neuroprotection
  • Reduces brain fog and mental fatigue
  • Improves blood flow to the brain


  • Consistent use is required
  • May not be suitable for sensitive users


In our opinion, the above supplements are definitely a reliable alternative for Alpha Brain as they contain a good selection of ingredients that all have an excellent safety profile. These options are also very effective in their function as they provide complete cognitive enhancement and improved mental processing, with some options even providing users with emotional support.

Upon investigation, we found that these supplements also positively affect physical functionality, making them beneficial choices. 

Frequently Asked Questions

Are nootropic aids effective?

Although there is no concrete proof that specific nootropic aids work, there is ample evidence and research that suggest the ingredients in the pills have a significant effect on cognitive functioning. They provide the brain with minerals, vitamins, and other compounds that improve brain health as well.

Are brain supplements safe to use?

Yes, natural supplements contain FDA-approved ingredients in clinically sound doses, which means it has an excellent safety profile. This allows the supplements to be safely integrated into short or long-term supplement plans.

Are nootropic aids approved by the FDA?

Natural nootropic supplements are typically not individually approved by the FDA. However, each ingredient in their formula is evaluated for its safety and given the FDA stamp of approval.

Can nootropics supplement use cause brain damage?

No. Users who adhere to dosage and usage guidelines will not be in danger of brain damage. However, if users misuse nootropic supplements, it may lead to serious consequences.

Does nootropic supplement use come with side effects?

Natural nootropic use is not associated with any serious/long-term side effects. However, some users may experience mild headaches, nausea, diarrhea, heartburn, or abdominal cramps. These side effects often disappear shortly after users get familiar with the substance in the body.


About the author 

Laurence Lee

Lee is a neuroscientist who has dedicated his career to understanding the inner workings of the brain. He has seen firsthand the power of these supplements in improving cognitive function and believes that more people should be aware of their benefits. In his articles, Lee shares his extensive knowledge on the subject and provides unbiased reviews of different products.

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